Abstract

AbstractAn 8‐year‐old male neutered golden retriever diagnosed with a T‐cell lymphoma and treated with a modified LOPP (lomustine, vincristine, prednisolone and procarbazine) protocol was presented to a referral hospital for management of an accidental overdose of lomustine (180 mg/m2). This overdose resulted in a severe myelosuppression with neutropenia and thrombocytopenia. The human platelet stimulator eltrombopag was used as part of the treatment protocol, alongside granulocyte‐macrophage colony‐stimulating factor and supportive care. The dog made a good recovery and completed a course of chemotherapy, achieving complete clinical remission of the lymphoma and long‐term survival (613 days).

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