Abstract
BackgroundSquamous cell carcinoma (SCC) is the most common oral cavity malignant tumor. Surgery, radiotherapy, and chemotherapy have been the major options for its treatment. Electrochemotherapy (ECT) is a novel local treatment successfully used in secondary or primary skin or subcutaneous tumors. This new cancer treatment is a modality in which a locally applied electrical field enhances cell membrane permeability, thereby allowing greater intracellular accumulation of a chemotherapeutic agent.MethodsWe report a case of a man affected by an ulcerated SCC. The man was treated with ECT with good results.ResultsIn our case, ECT was successful in the management of extensive metastasis of SCC in clinical conditions, whereas other approaches were rejected.ConclusionThis case shows good clinical results; however, other studies are necessary to show that ECT should be considered as a promising treatment option. © 2014 The Authors. Head & Neck Published by Wiley Periodicals, Inc. Head Neck 36: E86–E90, 2014
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