Abstract

The study is given to the use of dynamic regression model for reduction of shortages in drug supply: Purpose – the use of a dynamic regression model to identify the influence of lead-time on the reduction of time delays in drugs supply. To reach the goal, the author focuses on the improvement of drugs availability and the minimisation of time delays in drugs supply. Research methodology – the application of dynamic regression method to minimise shortage. The author suggests a dynamic regression model and accompanies it with autocorrelation and heteroskedasticity tests: Breush-Godfrey Serial Correlation LM Test for autocorrelation and ARCH test for heteroskedasticity. Findings – during analysis author identifies the relationship between lead-time and time delays in drugs supply. The author delivers a specific regression model to estimate the effect of deterministic lead-time on shortage. Probability F and Probability Chi-Square of this testing show that there is no significant autocorrelation and heteroskedasticity. Research limitations – the research is delivered for a one-month time frame. For the future, the study could review other periods. The author has incorporated the lead-time component in shortage reduction study by leaving capacity uncertainty component unresearched. The future studies could incorporate both elements into shortage reduction case analysis. Practical implications – presented framework could be useful for practitioners, which analyse drug shortage reduction cases. The revision of supply time table is recommended for pharmacies aiming to minimise the shortage level. Originality/Value – the analysis of deterministic lead-time and identification that the periodicity of shortage is evident each eight days. The study contributes to lead-time uncertainty studies where most of the authors analyse the stochastic lead-time impact on shortages.

Highlights

  • Shortages of medicines put patients at risk to get the most efficient health improvement

  • Practical implications – presented framework could be useful for practitioners, which analyse drug shortage reduction cases

  • The results showed the tendencies of shortage cases appearance and bring a solution for their minimization

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Summary

Introduction

Shortages of medicines put patients at risk to get the most efficient health improvement. There are political, economic, historical, environmental and other reasons causing shortage. Many pharmaceutical manufacturers import raw components from India, China and Europe. If some of these foreign suppliers have supply disruption (Newman, 2016) due to political, economic, historical (Coomber, Moyle, & South, 2016), environmental issues, this could cause shortage. Manufacturers may reduce their production volumes or cease the production. By stating above mentioned reasons in studies, authors usually face the problem that it is not easy to provide solution which could help to minimize the impact on patients

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