Use of Densitometric Indicators Free DICOM-Viewer’s and Digital Data Processing Programs in Surgical Treatment of Patients with Pulmonary Tuberculosis

Abstract

Objective — to determine the potential of using freely distributed specialised digital data processing programs and free DICOM-viewers for assessing densitometric indicators obtained from computed tomogra­phy of the thoracic organs. This aims to facilitate the planning of surgical treatment for patients with pulmonary tuberculosis and to substantiate methods for preventing pulmonary-pleural complications. Materials and methods. A retrospective analysis was conducted on the examination and treatment results of 103 patients with specific tuberculous lesions of the lungs. Histological examination of the resected material determined the degree of the specific inflammatory process in the affected tissue, based on which patients were categorised into groups. Group I included 32 patients with low activity of the specific inflammatory process, Group II comprised 37 patients with moderate activity and Group III included 34 patients with high activity. Using five common digital processing programs, densitometric indicators of the thoracic organs' structures were obtained. The accuracy of density indicators displayed by these programs was analysed in comparison with the results of histological examinations. Results and discussion. According to our data, the densitometric indicators obtained using free DICOM-viewers and digital data processing programs show a strong correlation with the reference standard and among themselves. The determined density indicators have a strong association with histological findings of emphysema and fibrosis of the lung parenchyma. These indicators are reliably identified both in cases of high activity of specific inflammation in the lung parenchyma and in inactive processes, allowing for patient stratification. It was found that the average density values of the mediastinal lymph nodes in cases of inactive specific inflammatory processes in 80 % of cases were (54.4 ± 17.8) HU. Values of (15.0 ± 2.5) HU characteri­sed high activity of specific inflammatory processes and the progressive phase of the disease. Clinically, 89 (86.4 %) of the patients with significant deviations in the densitometric density indicators of the lung parenchyma from the norm experienced prolonged air leakage in the postoperative period. In 96 (93.2 %) patients with altered density of mediastinal lymph nodes, prolonged postoperative exudation through pleural drains was noted. Patients with altered densitometric indicators had complicated intraoperative and postoperative courses. Changes in the density of the lung parenchyma detected on computed tomography of the thoracic organs were confirmed in 96.1 % of cases by histological examination of the resected material. These changes were reliably detected by all the programs studied. Conclusions. Densitometric indicators obtained using DICOM-viewers and digital data processing programs enable the planning of surgical treatment for patients with pulmonary tuberculosis and the reasoned application of methods to prevent pulmonary-pleural complications.