Use of Collagen-glycosaminoglycan Silicone Bilayer Matrix for Closure of Post-Mohs Micrographic Surgery Defects on the Nose: A 5-case Series

Abstract

Introduction. The use of dermal matrices has shown to be reliable and less invasive than skin grafts or skin flaps for wound management. This case series reports the clinical outcomes of 5 patients with defects on the nose post-MMS managed using collagen-glycosaminoglycan silicone bilayer matrix. Materials and Methods. Patient 1 had a BCC of the left nasal lateral sidewall, patient 2 had a BCC of the right nasal ala, patient 3 had a BCC of the nasal dorsum, patient 4 had a BCC of the left medial canthus, and patient 5 had a BCC of the left alar lobule of the nose. Layers of dermal matrix were stacked to augment soft tissue coverage in patient 5. Results. All patients had spontaneous epithelialization of the nose defects following dermal matrix placement. Time to healing ranged from 4 to 11 weeks after dermal matrix placement for defects ranging from 1.44 cm2 to 6.16 cm2. The covering was stable and resulted in satisfactory cosmesis at time of complete epithelialization. Conclusions. Closure of post-MMS nasal defects using bilayer matrix represents a viable option and an advantage over alternative forms of surgical repair when considering cosmesis and patient satisfaction.