Use of bovine plaque-rich plasma in piglets after the castration process

Abstract

Platelet-rich plasma (PRP) is a platelet concentrate obtained from whole blood centrifugation, widely used in human and veterinary medicine because it contains growth factors that enhance the tissue repair process. The PRP of autologous origin is the most used in the routine, however, the impossibility of obtaining autologous blood must be considered, proceeding with a PRP of homologous or heterologous origin. To evaluate the efficiency of heterologous PRP in wound healing and possible reactions caused by the application, 24 piglets were submitted to the surgical castration process and divided into 2 groups, with G1 the control group and G2 the group that received topical application at the site of heterologous PRP incision. Bovine blood samples were used to obtain PRP, which were processed following a double centrifugation protocol. The wounds were evaluated for 3 days and showed no significant difference in the onset of infection, swelling, redness and formation and crusting. The presence of pruritus was more significant on the first day of infection, which may be related to heterologous PRP. Thus, it was concluded that the evaluated signs are compatible with the physiological healing of the lesions, with no adverse reactions observed.