Abstract
FD Martinez, VM Chinchilli, WJ Morgan. Lancet. 2011;377(9766):650–657 To determine the effectiveness of inhaled beclomethasone dipropionate when used as a rescue treatment for symptoms in children with mild persistent asthma. Children and adolescents aged 5 to 18 years with well-controlled mild persistent asthma were enrolled from 5 clinical centers in a 44-week, randomized, double-blind, placebo-controlled trial. Participants who remained well controlled during the 4-week run-in period were stratified according to clinical center and age group and randomly assigned to 1 of 4 treatments: twice-daily beclomethasone with beclomethasone plus albuterol as rescue (combined group); twice-daily beclomethasone with placebo plus albuterol as rescue (daily beclomethasone group); twice-daily placebo with beclomethasone plus albuterol as rescue (rescue beclomethasone group); and twice-daily placebo with …
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