Use of antibiotics during the COVID-19pandemic.

Abstract

Interest has been shown in the use of antibiotics during the COVID-19pandemic. In this article we present the consumption of systemic antibiotics in Norway during the period of the pandemic. Total sales of systemic antibiotics in defined daily doses (DDD) were retrieved from the wholesaler-based medicinal product statistics for 2019 and 2020, and sales of antibiotics for use outside of healthcare institutions were retrieved from the Norwegian prescription database. Information was retrieved on the proportion of users (prevalence), doses (measured in DDD) and prescriptions. Total sales of systemic antibiotics increased in March 2020, but sales to persons outside of healthcare institutions did not. Compared to previous years, both total consumption and use of antibiotics outside of institutions fell steeply in the months that followed. The reduction was greatest for antibiotics against respiratory infections and in the youngest age groups. The significant reduction in the use of systemic antibiotics during the COVID-19pandemic is attributed to infection control measures and reduced contact with the health service. In 2016, the Norwegian government set a goal for a 30% reduction in antibiotic use by the end of 2020. The pandemic has contributed to the achievement of that goal.