Abstract
A multi-centre, open, within-patient controlled study was performed on 23 adult burnt patients to investigate the effectiveness, safety and tolerability of Veloderm ® in comparison with Algisite M™ and Jaloskin ® in split-thickness skin graft donor site care. The areas dressed with Veloderm ® completely healed within 10–13 days in a significant higher proportion than the other two dressings (47.6% for Veloderm ® versus 26.3% for Algisite M™ and 10% for Jaloskin ®, P < 0.03), showing during the whole study less incidence of exudates and of peri-lesional erythema. The aesthetic outcome of the treated lesions after healing was significantly better for Veloderm ® ( P = 0.0016). Veloderm ® and Jaloskin ® required very few renewals of the medication during the first week of treatment, while Algisite M™ needed several multiple re-dressings. Veloderm ® was judged better than the other two treatments as far as the acceptability ( P < 0.001), ease of use ( P < 0.001) and efficacy ( P < 0.00001). Both pain during application or at removal of dressings and local infections were negligible with all treatments. No scars were formed in any skin donor site. In conclusion Veloderm ® is a safe and effective dressing for the re-epithelialization of the skin graft donor sites: it showed higher activity than the other two compared dressings.
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