Use of a genetic navigator to maximize Lynch syndrome detection in women with endometrial and non-serous/mucinous ovarian cancer

A Lytwyn,A Tone,M Cesari,E Van De Laar,A Pollett,D Vicus,M Aronson,J Lerner-Ellis,L Eiriksson,R.H Kim,T Hart,B.A Clarke,S Holter,S.E Ferguson

doi:10.1016/j.ygyno.2020.06.064

Use of a genetic navigator to maximize Lynch syndrome detection in women with endometrial and non-serous/mucinous ovarian cancer

A Lytwyn, A Tone + Show 12 more

https://doi.org/10.1016/j.ygyno.2020.06.064

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Journal: Gynecologic Oncology

Publication Date: Oct 1, 2020

Affiliation: Juravinski Hospital, Hamilton Health Sciences, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Sunnybrook Health Science Centre, Mount Sinai Hospital, Toronto Metropolitan University

#Uptake Of Genetic Counselling #Immunohistochemistry For Mismatch Repair Proteins + Show 8 more

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Abstract

Objective: Despite recommendations for reflex immunohistochemistry (IHC) for mismatch repair (MMR) proteins to identify Lynch syndrome (LS), uptake of genetic counselling by those who meet referral criteria is low. Our objective was to use a multipronged approach including a genetics navigator to increase uptake of genetic testing for LS in endometrial (EC) and nonserous/mucinous ovarian cancer (OC) patients.

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