Use CPET data to predict the intervention effect of aerobic exercise on young hypertensive patients

Abstract

The incidence of hypertension has recently shown a significant increase in young people, with aerobic exercise intervention being recognized as an effective approach to decrease blood pressure (BP). However, BP response to aerobic exercise can be highly individualized, and no research has been conducted on predicting the effect of aerobic exercise intervention for reducing BP in young hypertensive patients. In this work, we use the data generated from a cardiopulmonary exercise test (CPET) in young hypertensive patients (before aerobic exercise intervention) to derive information from multiple cardiopulmonary metabolic indices. The data, presented as time series, are then analyzed by a machine learning method to predict the effect of aerobic exercise intervention in lowering BP. This study provides several novel insights for making personalized aerobic exercise intervention programs for young adults with stage I hypertension.