Abstract
Abstract Objectives The aim of this study was to review studies describing the use and the impact of technology-assisted workflow (TAWF) systems for drug compounding in hospital pharmacy. Content This is a scoping literature review. A search was conducted on studies describing or evaluating the use of TAWF published from January 1st, 2015 to July 31st, 2021. Two databases were searched (PubMed and Embase), followed by a search on Google Scholar. Summary 218 articles were screened and 17 were identified as meeting the inclusion criteria. TAWFs all included preparation assistance software (17/17), barcode reader (17/17), photo or video taking (17/17), and some included gravimetric systems (8/17), and the use of robots (2/17). A majority of the studies included used technology for parenteral preparations (15/17, one for oral preparations only (1/17), and one used technology for both types of preparations (1/17). Most of the articles selected presented drugs prepared for adults (10/17), the others presented drugs intended for children (4/17) or for a mix of adults and children (3/17). Four parameters were evaluated: error detection rate (n=15), preparation and validation time (n=7), and costs generated or saved (n=7). Ten studies evaluated the pre-post impact of implantation of a TAWF (10/17). Outlook Given the heterogeneity of the data available, the use of TAWF was associated with an increased ability to detect preparation errors, a reduction in preparation time and costs, and increased satisfaction of pharmacy technicians and pharmacists. However, better quality studies are needed to confirm the positive impacts studied.
Highlights
A search was conducted on studies describing or evaluating the use of technology-assisted workflow systems (TAWF) published from January 1st, 2015 to July 31st, 2021
Outlook: Given the heterogeneity of the data available, the use of TAWF was associated with an increased ability to
Drug compounding is defined as the “process of combining, mixing, or altering ingredients to create a medication tailored to the needs of an individual patient
Summary
Drug compounding is defined as the “process of combining, mixing, or altering ingredients to create a medication tailored to the needs of an individual patient. The Food and Drug administration insists that “compounded drugs can serve an important medical need for patients, but they do not have the same safety, quality, and effectiveness assurances as approved drugs. Unnecessary use of compounded drugs unnecessarily exposes patients to potentially serious health risks.” [1]. Several authors have identified the risks associated with drug compounding, such as microbial contamination to patients, wrong manipulation or overdose [2,3,4,5]. Unlike the pharmaceutical industry, which must comply with good manufacturing practices to commercialize approved drugs in a given country, most countries and professional regulatory authorities supervise drug compounding produced by pharmacists with less demanding professional standards [6]
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