Abstract

To achieve compliance with the revised World Health Organization International Health Regulations (IHR 2005), countries must be able to rapidly prevent, detect, and respond to public health threats. Most nations, however, remain unprepared to manage and control complex health emergencies, whether due to natural disasters, emerging infectious disease outbreaks, or the inadvertent or intentional release of highly pathogenic organisms. The US Centers for Disease Control and Prevention (CDC) works with countries and partners to build and strengthen global health security preparedness so they can quickly respond to public health crises. This report highlights selected CDC global health protection platform accomplishments that help mitigate global health threats and build core, cross-cutting capacity to identify and contain disease outbreaks at their source. CDC contributions support country efforts to achieve IHR 2005 compliance, contribute to the international framework for countering infectious disease crises, and enhance health security for Americans and populations around the world.

Highlights

  • To achieve compliance with the revised World Health Organization International Health Regulations (IHR 2005), countries must be able to rapidly prevent, detect, and respond to public health threats

  • Following the 2002–2003 severe acute respiratory syndrome (SARS) coronavirus outbreak, which demonstrated how rapidly a pathogen could spread to 26 countries [1], the World Health Organization (WHO) in 2005 adopted the revised International Health Regulations

  • The 2009 pandemic of influenza A(H1N1) resulted in the first declaration of a public health emergency of international concern under IHR 2005 [3] and provided new evidence that the world was ill prepared for a global health crisis

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Summary

US Centers for Disease Control and Prevention and Its

To contain health threats and ensure global health security, all countries must rapidly detect and respond to public health emergencies and, when overwhelmed, call upon global deployment capacity This need is clearly evident, as the world is more susceptible to infectious disease threats due to increased international travel and trade, spread of newly emerging or reemerging microbes, and inadvertent release of dangerous pathogens from laboratories or bioterrorism acts. Numerous threats followed H1N1, including cholera in post-earthquake Haiti in 2010 [4]; Middle East respiratory syndrome coronavirus in Saudi Arabia in 2012 [5] and its exportation to the Middle East, Europe, Asia, and the United States; West Africa Ebola virus disease in 2014 [6]; chikungunya virus in 2013 and Zika virus in 2015 in the Americas [7]; and yellow fever virus reemergence in Africa, China, and Brazil in 2015 [8] Despite these serious threats, only 33% of WHO member states had self-reported IHR 2005 compliance by December 2014 [9]. Global Health Security Agenda (GHSA), that strengthen emergency mitigation and capacity-building partnerships dedicated to containing threats at their sources

Emergency Mitigation of Global Health Threats
Vaccinations of health workers in Ebola trial
New diagnostic tests established in national or regional laboratories
Findings
Persons across the globe served by NPHIs
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