Abstract

Urtica dioica belongs to the Urticaceae family and is found in many countries around the world. This plant contains a broad range of phytochemicals, such as phenolic compounds, sterols, fatty acids, alkaloids, terpenoids, flavonoids, and lignans, that have been widely reported for their excellent pharmacological activities, including antiviral, antimicrobial, antihelmintic, anticancer, nephroprotective, hepatoprotective, cardioprotective, antiarthritis, antidiabetic, antiendometriosis, antioxidant, anti-inflammatory, and antiaging effects. In this regard, this review highlights fresh insight into the medicinal use, chemical composition, pharmacological properties, and safety profile of U. dioica to guide future works to thoroughly estimate their clinical value.

Highlights

  • Genus Urtica, commonly known as “nettle,” is a medicinal plant belonging to the family Urticaceae with multiple health benefits that have been used medicinally since at least the times of Ancient Greece [1]

  • This review aims to provide an overview of the botanical features, chemical composition, and biological effects of Urtica species towards well-being promotion and disease prevention

  • Results of this study indicated that both treatments were effective in mitigating clinical symptoms occurring due to acute arthritis. ese results are of great importance for patients who suffer from nonsteroidal anti-inflammatory drugs (NSAIDs) intolerance because of ulceration or other gastric problems

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Summary

Introduction

Genus Urtica, commonly known as “nettle,” is a medicinal plant belonging to the family Urticaceae with multiple health benefits that have been used medicinally since at least the times of Ancient Greece [1]. It has been revealed to be extremely useful for the treatment of microbial and parasitic infections, cancer, jaundice, stomach diseases, snakebites, diabetes, liver and kidney problems, wounds, diuretic, libido, pulmonary diseases, hypotensive, blood purification, urticaria, allergic rhinitis, prostate disorders, hemorrhoids, and galactagogue and as a depurative Apart from this, these species have been reported to be used for exorcism, postcalving care, sprains, bones fracture, hematuria, neck sore, and yolk sore [2, 12,13,14,15,16,17,18,19,20,21,22,23,24,25,26]

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