Abstract

熊去氧胆酸(UDCA)在肝移植后主要拮抗疏水性胆汁酸的细胞毒性,但其对肝移植患者的保护作用尚存争议[1].本研究观察了华西医院127例肝移植术后患者使用UDCA的临床资料,现报道如下.一、资料与方法1.研究对象:收集我院2002年1月-2009年3月712例肝移植患者.术后平均随访35个月,随访方案采用移植术后3月内每半月随访1次,术后3~6个月患者每月随访1次,术后6~ 12个月患者每2个月随访1次,术后1年以上患者每3个月随访1次.符合本实验入组条件者127例(1例患者因不良反应退出研究). 关键词:熊脱氧胆酸;缺血再灌注损伤;肝移植

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