UROLOGICAL COMPLICATIONS AFTER KIDNEY TRANSPLANTATION: INCIDENCE AND RISK-FACTORS

Abstract

P309 Aims: The purpose of this study was to determine the incidence and management of urological complications. The possible risk factors from donor, graft and recipient for were ascertained for development of urological complications. Methods: Between 1992 and 2004, 974 patients underwent renal transplantation in our hospital. The patients with urological complications from this group were compared to a random sample of 357 patients without urological complications. Donor, graft and recipient characteristics, as well as implantantion procedure were scored. The incidence and type of complication were described and risk factors for urological complications were determined by chi-square tests and univariate analysis. Results: There were 78 (8.0 %) patients with urological complications. The complications were urinary leakage in 14 (1.4%), ureteral obstruction in 25 (2.6%), stenosis in 22 (2.3%) and hydronefrosis in 17 (1.7%). Age and cause of death were not related to urological complications. A relevant risk-factor for development of urological complications was mean systolic blood pressure of donor during last 24 hours. Two and threeway interactions were found for urine output in the last hour, systolic blood pressure and the occurence of hypotensive episodes. Ureter, venous and arterial abnormalities were not related to urological complications, nor were atherosclerosis, vascular problems or surgical bleeding. Conclusions: The incidence of urological complications was 8%. Urine output, systolic blood pressure and the occurence of hypotensive episodes of the donor combined have a strong additive effect on the occurence of urological complications. Donor and recipient characteristics and implantation problems showed no relation with the occurence of urological complications.