Abstract
3A two years old girlwith newly diagnosed acute lymphoblastic leukemia on induction chemotherapy developed abdominal colic and passage of powdery material in the urine. Ultrasound abdomen revealed stone in the right kidney. She was treated with adequate hydration and alkali therapy andimprovedsymptomatically. She has completed intensive phase of chemotherapyand had no recurrence of symptoms. Repeat ultrasound after two months of therapy showed no stones. Though renal stone disease is rare in childhood leukemia, it should be ruled out, as abdominal colic is generally attributed to the common side effects of drugs used in chemotherapy.
Highlights
The incidence of renal stone disease in children is showing increasing trend due to various factors
We present a child with acute lymphoblastic leukemia who developed abdominal colic during induction phase, turned out to be renal stones and treated conservatively
Howard et al had reported an incidence of 0.9% of urolithiasis among pediatric patients with Acute Lymphoblastic Leukemia (ALL) where as Mariane et al Pediatric Review: International Journal of Pediatric Research Aailable online at: www.pediatricreview.in 755|P a g e had reported an incidence of 3.4% among his study population of 12 children [3,4]
Summary
The incidence of renal stone disease in children is showing increasing trend due to various factors. We present a child with acute lymphoblastic leukemia who developed abdominal colic during induction phase, turned out to be renal stones and treated conservatively. The child had a stormy course in first 2 weeks of induction therapy She developed pneumothorax and pneumomediastinum and needed left sided inter costal drainage. In view of persistence of abdominal pain and as mother noticed intermittent passage of powdery material in urine, USG abdomen was done which showed a 1.8 x 0.7cm stone in the right renal pelvis (fig 1). She did not have fever, hematuria, passage of stone, dysuria, urgency and increased frequency of urination. On follow up after threemonths, repeat ultrasound was normal with no evidence of renal stones (fig 2)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
