Abstract
High-dose urography should be considered an essential part of the management of most patients with advanced uremia. With increased acceptance and use of doses in the range of 1 ml. per pound, the acquisition of useful diagnostic information has been the rule rather than the exception. When high doses were first used, there were a number of contraindications to the procedure, but as favorable experience has accumulated, these contraindications have been relaxed. The few reports of serious adverse responses to urography in uremic patients can be attributed, in large part at least, to fluid deprivation or hypovolemia preceding the examination.
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