Urodynamics parameters in female urinary incontinence patients with pelvic organ prolapse

Abstract

Objective To compare the urodynamic parameters in female patients with incontinence with or without pelvic organ prolapse. Methods The urodynamic data from 140 patients diagnosed urinary incontinence and another 42 patients coexisted with pelvic organ prolapse were reviewed and analyzed. The urodynamics parameters were compared in perfusion, urination, bladder compliance, maximum urinary flow rate （Qmax）, detrusor muscle pressure of maximum urinary flow rate （Pdet,Qmax）, minimum urinary flow rate（Pdet, Qmax）, urethral resistance factor （RUA）, obstruction of bladder index （OBI） and normalized detrusor contractility. The influence of pelvic organ prolapses with incontinence on bladder filling and voiding function was evaluated also.Results There were no significant differences between 140 patients of urinary incontinence and 42 patients coexisted with pelvic organ prolapse in perfusion （P=0.142）, bladder compliance （P=0.273）, Qmax（P=0.192）,Pdet （P=-0. 629）, Qmin （P=0.365） and normalized detrusor contractility （P=0.380）. There were significant differences in age（P=2.2×10^-5）, urination（P=0.034）, Pdet.Qmax（P=0.045）, RUA（P=0.018）, OBI （P=0.017）. Conclusions There is not clinically significant change in urine storage function of bladder in patients with pelvic organ prolapse, but the parameters of voiding function of bladder may existe difference. The increased bladder outlet resistance and postvoid residual urine are noticed in patients with pelvic organ prolapse. Key words: Pelvic organ prolapse; Urinary incontinence; Urodynamic parameters