Abstract

The aim of study was the investigation of frequency and clinical significance of selected stereotypical recurring urodynamic patterns, which are manifested by the results of a complex urodynamic study in patients with idiopathic overactive bladder. The combined urodynamic study (CUS) was conducted in 137 patients with IOAB. The standard cystotonometry allowed to observe the maximum cystometric capacity. It also allowed to determine the bladder sensitivity (BS) and detect the presence of detrusor overactivity (DO). The results of retrograde cystotonometry established three variants of detrusor overactivity: phase DO, terminal DO, and stress-induced DO. The study of the bladder function using methods of UFM and EMG of anal sphincter in the emptying phase, confirmed the association of obstructive urination with incomplete discharge of the urethra from the effects of the sphincter. The coordination of function of the detrusor and external sphincter were assessed according to the results of CUS and sphincteric EMG. The EMG analysis in Work / Rest Assessment mode allowed to reveal the characteristic changes in the biopotential indices of the pelvic sphincter and indicated their correlation with the clinical features of the disease course. The imperative character of urination was established in 137 patients with IOAB during CUS characterized by hyperactivity and hypertensity of bladder, depending on the severity of the violation of the integrative function of LUT.

Highlights

  • Overactive Bladder (OAB), known as Overactive Bladder Syndrome, is a condition of frequent feel to urinate which adversely affects the quality of life

  • Purpose of the Study The purpose of the study was to determine the frequency and clinical significance of selected stereotypical recurring urodynamic patterns, which are manifested by the results of urodynamic studies in patients with idiopathic overactive bladder

  • The imperative character of urination was established in 137 patients with idiopathic overactive bladder (IOAB) during combined urodynamic study (CUS) characterized by overactivity and hypertensity of bladder, depending on the severity of the violation of the integrative function of LUT

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Summary

Introduction

Overactive Bladder (OAB), known as Overactive Bladder Syndrome, is a condition of frequent feel to urinate which adversely affects the quality of life. Frequent urges for urination may occur at the day, at night, or both, with urinary incontinence (UI) or without it [1]. The overall prevalence of OAB is similar between men and women, there are sex-specific differences in the prevalence of various symptoms within the OAB complex [2,3,4]. Anatomical and physiological differences in the lower urinary tract of males and females may help to explain these variations. OAB prevalence rates in large population-based studies range from 7-27% in men and 9-43% in women. A proportion of OAB cases (37-39%) has correlated during a given year, but the majority of patients had persistent symptoms [5,6]

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