Abstract
Case report We report the case of a 28-year-old female who developed acute generalized urticaria and facial angioedema one hour after ingesting grapes of several varieties. The reaction was treated at Emergency Room level with parenteral administration of corticoids and anti-histamines. She previously ingested grapes and other fresh fruits with no reaction and denied rhinitis complaints. Skin prick tests with a large battery of aeroallergens, including latex, were positive to peach LTP, peach, apple, and plum but were negative with grape commercial extract. Prick by prick procedure performed with the pulp and peel of a variety of red and white grapes yielded positive results, as well as with fresh cherry. Specific IgE (kUA/l; ImmunoCAP, Phadia) were present for peach (1.16), peach LTP (1.79), apple (1.17), plum (1.36) and cherry (0.8) and were negative for grape.
Highlights
Grape (Vitis vinifera) allergy is considered rare and usually found in association with pollinosis
Recent publications identified Vit v 1, a grape lipid transfer protein (LTP), as a major allergen that is sometimes involved in severe reactions
Prick by prick procedure performed with the pulp and peel of a variety of red and white grapes yielded positive results, as well as with fresh cherry
Summary
Grape (Vitis vinifera) allergy is considered rare and usually found in association with pollinosis. Uriticaria and angioderma after ingestion of grapes Ana Célia Costa1, Pedro Morais Silva1*, Maria Conceição Santos2, Manuel Pereira Barbosa1 From Food Allergy and Anaphylaxis Meeting 2011 Venice, Italy.
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