Abstract
Urinary infection or radiation cystitis? A prospective evaluation of urinary symptoms in patients submitted to pelvic radiotherapy
Highlights
The urinary bladder is frequently exposed, partially or entirely, during radiation therapy for pelvic tumors
The specific protocol of the study included an evaluation of the main urinary symptoms related to the treatment, which were graded according to Radiation Therapy Oncology Group (RTOG) scores [14]
Due to the lower than expected incidence of symptomatic patients and especially the low incidence of urinary tract infection (UTI) found in the study, which was much lower than that used for the sample calculation, patient recruitment was interrupted, and the initially proposed regression analysis of UTI-predictive factors was aborted
Summary
The urinary bladder is frequently exposed, partially or entirely, during radiation therapy for pelvic tumors. Due to the effect of radiation on epithelial cells, acute functional alterations, including increased urinary frequency, dysuria and hematuria, can occur and may mimic the secondary symptoms of urinary tract infection (UTI) [1]. Received for publication on June 24, 2019. Accepted for publication on September 24, 2019
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