Abstract
The urinary excretion of dopamine and homovanillic acid was investigated in 20 patients with acute myocardial infarction. The mean excretion of dopamine was increased during the first five days of the disease. The mean excretion of the metabolite of dopamine—homovanillic acid was also higher during the first days of myocardial infarction than in the subsequent period, although it did not exceed the upper limit of normal. No significant correlation between urinary dopamine and noradrenaline excretion was found. The results of the study are discussed in the light of the augmented sympathetic activity accompanying acute myocardial infarction.
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