Abstract
SummaryDeterminations of urinary 5-hydroxytryptamine (5-HT) and 5-hydroxy indoleacetic acid (5-HIAA) in x-irradiated rats (665 r) were performed.No significant association between the excretion of 5-HT and survival-time was found. However, the amounts of excreted 5-HIAA after irradiation, as well as the sum of 5-HT and 5-HIAA, gave a significant positive correlation with the survival-time.It seems that an intensive radiation-induced liberation of 5-HT, with its prompt degradation and excretion, might have a favourable influence on the fate of sub-lethally irradiated animals.
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