Abstract
Urinary epinephrine, norepinephrine and 17—OH—CS (17-hydroxycorticosteroid) levels were higher on the initial day of hospitalization than on subsequent occasions during hospital stay in two groups of normal young adults. A positive correlation was observed between the three hormones in this situation and the possible relationship of these findings to earlier related work in the monkey is discussed. Although group and individual differences in degree of response were noted, limiting the value of hospitalization as an experimental situation in psychosomatic research, the direction of change during hospitalization was quite consistent. It is also suggested that psychoendocrine responses to environmental change must be taken into account in the design of some control experiments in clinical research.
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