Urinary bisphenol A concentration in children with Attention-deficit/hyperactivity disorder : a pilot study

Abstract

Background: Childhood developmental disorders and related problems such as learning disabilities and attention deficit hyperactivity disorder (ADHD) account for a growing burden on communities. Problems of child behavioral development could be caused by BisphenolA (BPA) in addition, westernization have the potential toinfluence its exposure.Exposure to BPA remains poorly characterizedin the developing countries so, in this pilot study, weevaluate BPA exposure and assess somesources of exposure among Egyptian children. Method: We measured total urinary BPA concentrations in spot samples in ADHD (N = 24) and healthy (N = 24) Egyptian children. We also collected questionnaire data regarding food storage behaviors to assess potential sources of exposure.Results: ADHD Egyptian children exhibited higher urinary BPA concentrations; with median value of 24.5 µg/L. Reported consumption of canned food wasa significant predictor of increasing concentrations of urinary BPA.Conclusions: The relatively high urinary BPA concentrations within Egyptian children with ADHD and the significantassociation between the canned foodconsumption and the increased urinary BPA concentration highlights the need to modify food and consumer product patterns to prevent potential adverse health outcomes in the future. Keywords: ADHD, Egyptian, children, Bisphenol A, canned food