Abstract
Normal human urine was inoculated with pure cultures of various urinary pathogens, and then incubated at 37°. Organic acids were measured in the urine by gas Chromatographie techniques. Microorganisms of 11different species were found capable of producing large amounts of acetic acid in urine, while 8 species produced propionic acid. Bacteria of 8 different species were able to hydrolyze hippuric acid to benzoic acid. A few organisms also produced butyric, isovaleric, or caproic acid. Thus investigators who study cases of presumed metabolic disorders in man must exclude the possibility that abnormal acids found in urine are only artifacts produced by urinary tract infections.
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