Abstract
Renal transport of urate is influenced by many endogenous metabolites and drugs. Any drug whose net effect on renal tubular transport of urate results in increased urate clearance can be considered a uricosuric agent. By this definition, uricosuric drugs include a large number of compounds with diverse chemical structures and pharmacologic properties. Only a few of these drugs have been widely employed clinically as uricosuric agents.KeywordsUric AcidProximal TubuleSerum Uric AcidHepatic UptakeEthacrynic AcidThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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