Abstract
IntroductionA rising incidence of kidney stone disease has led to an increase in ureteroscopy (URS) and shock wave lithotripsy (SWL). Our aim was to compare the cost of URS and SWL for treatment of stones.MethodsA systematic review and meta-analysis based on Cochrane and PRISMA standards was conducted for all studies reporting on comparative cost of treatment between URS and SWL. The cost calculation was based on factual data presented in the individual studies as reported by the authors. English language articles from January 2001 to December 2017 using Medline, PubMed, EMBASE, CINAHL, Cochrane library and Google Scholar were selected. Our study was registered with PROSPERO (International prospective register of systematic reviews)—registration number CRD 42017080350.ResultsA total of 12 studies involving 2012 patients (SWL-1243, URS-769) were included after initial identification and screening of 725 studies with further assessment of 27 papers. The mean stone size was 10 and 11 mm for SWL and URS, respectively, with stone location in the proximal ureter (n = 8 studies), distal ureter (n = 1), all locations in the ureter (n = 1) and in the kidney (n = 2). Stone free rates (84 vs. 60%) were favourable for URS compared to SWL (p < 0.001). Complication rates (23 vs. 30%) were non-significantly in favor of SWL (p = 0.11) whereas re-treatment rates (11 vs. 27%) were non-significantly in favor of URS (p = 0.29). Mean overall cost was significantly lower for URS ($2801) compared to SWL ($3627) (p = 0.03). The included studies had high risk of bias overall. On sub-analysis, URS was significantly cost-effective for both stones < 10 and ≥ 10 mm and for proximal ureteric stones.ConclusionThere is limited evidence to suggest that URS is less expensive than SWL. However, due to lack of standardization, studies seem to be contradictory and further randomized studies are needed to address this issue.
Highlights
A rising incidence of kidney stone disease has led to an increase in ureteroscopy (URS) and shock wave lithotripsy (SWL)
To 2 cm in the kidney are suitable for both URS and SWL, several prospective randomized controlled trials have demonstrated the superiority of URS over SWL in terms of stone free rate (SFR) and retreatment rates [4]
Majority of stones might be amenable for either URS or SWL and treatment is tailored after patient counseling, for patients suitable for both modalities, a major factor in treatment selection is the cost associated with it, especially with healthcare resources already stretched to its limit
Summary
A rising incidence of kidney stone disease has led to an increase in ureteroscopy (URS) and shock wave lithotripsy (SWL). Majority of stones might be amenable for either URS or SWL and treatment is tailored after patient counseling, for patients suitable for both modalities, a major factor in treatment selection is the cost associated with it, especially with healthcare resources already stretched to its limit. These costs can vary greatly depending on the initial purchase price, cost of consumables and repair, durability of the instruments, the negotiated discounts available from manufacturers and the reimbursement received by the providers
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