Abstract
BackgroundIn most cases, prostate cancer metastasizes to the lymph nodes, bone, and liver. In very rare cases, it metastasizes to the ureter. Due to the difficulty in making a preoperative diagnosis, ureteral metastasis from prostate cancer is typically diagnosed after nephroureterectomy.Case presentationA 77-year-old Asian Japanese man with right hydronephrosis and hydroureter was referred to our hospital to undergo further examination due to the suspicion of ureteral cancer. He had been diagnosed 2 years previously with prostate cancer with a Gleason score of 4+5=9. He received radiotherapy and androgen deprivation therapy. A nephroureterectomy was performed for suspected right ureteral cancer. On the basis of a histopathological examination, poorly differentiated adenocarcinoma was suspected, and the tumor cells were positive for prostate-specific antigen immunohistochemically.ConclusionsWe herein report a rare case of ureteral metastasis in castration resistant prostate cancer.
Highlights
In most cases, prostate cancer metastasizes to the lymph nodes, bone, and liver
We report a rare case of ureteral metastasis in castration resistant prostate cancer
Due to the difficulty in obtaining a preoperative diagnosis, ureteral metastasis from prostate cancer is typically diagnosed on the basis of examination of nephron specimens obtained at ureterectomy
Summary
Prostate cancer metastasizes to the lymph nodes, bone, and liver. In very rare cases, it metastasizes to the ureter. Background In most cases, prostate cancer metastasizes to the lymph nodes, bone, and liver. Due to the difficulty in obtaining a preoperative diagnosis, ureteral metastasis from prostate cancer is typically diagnosed on the basis of examination of nephron specimens obtained at ureterectomy. We report an extremely rare case involving a patient with ureteral metastasis from prostate cancer.
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