Abstract
Using radioactive rubidium as a tracer of potassium, uptake of potassium aspartate in human blood cells in vivo was compared with that of potassium chloride.Small dosis of 42KCl and 86Rb Cl was injected rapidly into a cubital vein of four normokalemic patients with urologicl disease. Venous blood was drawn consecutively with certain intervals up to seven hours from the contralateral cubital vein. After each venous puncture, the blood was immediately separated into one ml. of whole blood and one ml. of plasma for measurement of the radioactivity.One week after the above experiment, the same procedure concerning 86Rb aspartate was repeated.Concentrations of the tracers in plasma and blood cells were calculated and the ratio of the two as well.The result showed uptake of rubidium aspartate was quicker than that of rubidium chloride in three patients out of four.It is concluded that potassium will be transported into blood cells more quickly when it is given as asparate than given as chloride.
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Schedule a callMore From: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology
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