Abstract
The neuroendocrine-endocrine systems that regulate insect post-embryonic development and reproduction are controlled by complex interendocrine regulatory mechanisms. For the juvenile hormone (JH) and ecdysteroid endocrine systems of the tobacco hornworm, Manduca sexta, these mechanisms function at various levels to modulate the synthesis/secretion of the JHs and ecdysteroids (Bollenbacher, 1988). One example is the brain-mediated control by 20-hydroxyecdysone (20-HE) of JH synthesis during larval-pupal development: the pupal commitment peak in the hemolymph ecdysteroid titer stimulates the post-commitment increase in JH acid synthesis by the CA (Watson et al., 1986), while the large pre-molt peak in the titer a few days later apparently inhibits synthesis (Granger et al., 1987).
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