Upregulation of the cfiA carbapenemase gene in a Bacteroides fragilis strain by the novel integrative and conjugative element Tn7563

Tore Taksdal Stubhaug,Nermin Zecic,Dagfinn Skaare

doi:10.1016/j.anaerobe.2023.102785

Upregulation of the cfiA carbapenemase gene in a Bacteroides fragilis strain by the novel integrative and conjugative element Tn7563

Tore Taksdal Stubhaug, Nermin Zecic + Show 1 more

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https://doi.org/10.1016/j.anaerobe.2023.102785

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Journal: Anaerobe	Publication Date: Sep 23, 2023
License type: cc-by

Affiliation: University of Oslo, Sykehuset i Vestfold

#Integrative And Conjugative Element #Bacteroides Fragilis Strain + Show 7 more

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Abstract

We describe Tn7563, a 31,844-bp integrative and conjugative element (ICE) carrying promoters upregulating the cfiA carbapenemase gene in Bacteroides fragilis strain Tbg-22. Excision and circularization of Tn7563 was demonstrated by PCR. Previously, only insertion sequences (IS) have been shown to carry mobile promoters for cfiA.

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