Upper limb ischemia at birth

Abstract

The aim of this case report: is to present and discuss the clinical features, diagnostic challenges, management strategies, and outcomes of two cases involving upper limb ischemia in neonates. By examining these cases, we aim to contribute to the understanding of the underlying causes, diagnostic pathways, and potential interventions for neonates presenting with upper limb ischemia, emphasizing the importance of early diagnosis and appropriate management to minimize complications and enhance patient outcomes. Discussion Summary: ABS presents a range of fetal abnormalities caused by fibrous bands in the womb, leading to deformities and developmental interruptions. Limb constriction rings are common, potentially resulting in limb loss or digit deformities. Neonatal limb ischemia, particularly acute limb ischemia, is rare but associated with catheterization. In utero compression ischemia, often affecting the brachial artery, can lead to limb ischemia. Risk factors include maternal conditions like diabetes, dehydration, and more. Proper delivery planning is crucial for macrosomic infants. Diagnosis and management of neonatal limb ischemia are challenging. Doppler ultrasound is the primary diagnostic tool, with fetal CT enhancing prenatal assessment. Thrombolytic therapy, including alteplase and heparin, is a common treatment.