Abstract

In the U.S., most bleeding peptic ulcers result from the use of nonsteroidal anti-inflammatory drugs (NSAIDs). Risk for gastrointestinal lesions is well established for prescription-strength NSAIDs but not for lower doses that are available over-the-counter (OTC). To estimate the risk for gastrointestinal toxicity with low-dose OTC NSAIDs, investigators, with industry funding, performed a retrospective case-control study. A total of 359 patients who …

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