Abstract
Concerns about painful or embarrassing diagnostic procedures have a negative effect on health-seeking behaviour. Endoscopy of the upper gastrointestinal tract is the investigation of choice for dyspepsia; yet, it is uncomfortable, often requires sedation, and is associated with the risk of intubation. Furthermore, although the demand for endoscopy is increasing, most examinations show no, minor, or irrelevant abnormalities. Therefore, it might be safer and more acceptable to use a non-invasive approach that identifies the few patients who need conventional endoscopy for biopsy.
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