Abstract
Blackberry fruit (Rubus spp. L., Rosaceae) is a source of natural antioxidants for cosmetic products due to its abundance of phenolic compounds. The aim of the present study was to characterize blackberry extracts of the cultivars ‘Tupy’, ‘Guarani’, and ‘Xavante’ and to develop niosomes loaded with blackberry extracts for future applications in cosmetic formulations. After fruit collection at the Experimental Central Stations of the Federal University of Parana, Quatro Barras, Brazil, the extracts were solubilized in different solvents. The choice of extraction solvent and blackberry cultivar was established by analysis to evaluate the total phenolic content, radical scavenging capacity, and chemical characterization by ultra-performance liquid chromatography couple to quadrupole time-of-flight-mass spectrometry. These tests revealed that fruits of Rubus ‘Xavante’ had the highest potential to be used as an active cosmetic ingredient. Niosomes formulated with the acetone/water extract obtained from the fruit of this cultivar showed both good performance and encapsulation efficiency. The results indicate that this type of niosome can be considered a promising delivery system with the potential to improve skin absorption, in addition to the antioxidant, anti-aging, and UV protective activities of the polyphenol-rich blackberry extracts.
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