Abstract
Background: Preoperative radiotherapy (RT) or chemoradiotherapy (CRT) followed by a total mesorectal excision (TME) has become the standard of care for locally advanced rectal cancer (LARC). The optimal timing of surgery after neoadjuvant CRT in LARC is still controversial. Aim of this study was to evaluate the effect of increasing time interval between the end of CRT and surgery on pathological outcomes.
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