Abstract
Non-melanoma skin cancers (NMSCs) are the most common malignancy worldwide, of which 99% are basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs) of skin. NMSCs are generally considered a curable diseases, yet they currently pose an increasing global healthcare problem due to rising incidence. This has led to a shift in emphasis on prevention of NMSCs with development of various skin cancer prevention programs worldwide. This article aims to summarize the most recent changes and advances made in NMSC management with a focus on prevention, screening, diagnosis, and staging.
Highlights
Non-melanoma skin cancers (NMSC), known as keratinocyte cancers, are the most common malignancy worldwide [1,2]
Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) of the skin make up 99% of all NMSC, with basal cell carcinomas (BCCs)
SCC is responsible for the majority of NMSC-related deaths [9]
Summary
Non-melanoma skin cancers (NMSC), known as keratinocyte cancers, are the most common malignancy worldwide [1,2]. Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) of the skin make up 99% of all NMSC, with BCC being 3 to 5 times more common than SCC [1,4,5,6,7]. Other much less common forms of NMSC include: Merkel cell carcinoma (MCC), primary cutaneous B-cell lymphoma, Kaposi sarcoma, carcinosarcoma, and dermatofibrosarcoma [6,8]. NMSCs are generally considered to be curable, they pose a vast problem for healthcare worldwide due to rising incidence [1,9,10,11]. SCC is responsible for the majority of NMSC-related deaths [9]
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