Abstract
Updated Recommendations for the Use of Varicella and MMR Vaccines In HIV-Infected Individuals: An Advisory Committee Statement (ACS) National Advisory Committee on Immunization (NACI)†.
Highlights
This National Advisory Committee on Immunization (NACI) statement updates the recommendations previously published in the Canadian Immunization Guide (CIG) 2006(1) for the use of varicella vaccine in individuals infected with the human immunodeficiency virus (HIV)
Pless (Centre de l’immunisation et des maladies respiratoires infectieuses). This NACI statement updates the recommendations previously published in the Canadian Immunization Guide (CIG) 2006(1) for the use of varicella vaccine in individuals infected with the human immunodeficiency virus (HIV)
Available studies to date have shown that HIVinfected children developed suboptimal responses to measles vaccine, with antibody response rates ranging from 25% to 70% post-vaccination.(9) As measles antibody titer is known to decline more rapidly over time in HIV-infected, as compared to HIV-uninfected children, a dose of immune globulin is recommended for prophylaxis in HIV-infected children after a known exposure to confirmed wild-type measles, even if there is a history of previous MMR immunization.(1),(9),(11),(12)
Summary
The National Advisory Committee on Immunization (NACI) provides the Public Health Agency of Canada with ongoing and timely medical, scientific and public health advice relating to immunization. Les recommandations d’utilisation et les autres renseignements qui figurent dans le présent document peuvent différer du contenu de la monographie de produit du fabricant du ou des vaccins au Canada. Desai (Centre for Immunization and Respiratory Infectious Diseases), LCol (Dr.) James Anderson (Department of National Defence), Dr Ezzat Farzad (First National and Inuit Health Branch - Office of Community Medicine), Dr J. FarhangMehr (Centre de l’immunisation et des maladies respiratoires infectieuses), Dre S. Desai (Centre de l’immunisation et des maladies respiratoires infectieuses), Lcol (Dr) James Anderson (ministère de la Défense nationale), Dre Ezzat Farzad (Direction générale de la santé des Premières nations et des Inuits - Bureau de la médecine communautaire), Dr J. Elliot (Centre de l’immunisation et des maladies respiratoires infectieuses), Dr P. Varughese (Centre de l’immunisation et des maladies respiratoires infectieuses), Dr R. Pless (Centre de l’immunisation et des maladies respiratoires infectieuses)
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