Abstract
Sepsis and septic shock are common critical diseases in the ICU, which have high mortality and seriously affect the patients′ quality of life.The Surviving Sepsis Campaign group pushed forward the Hour-1 Bundle concept which includes measuring lactate level, obtaining blood cultures prior to administration of antibiotics, administering broad-spectrum antibiotics, rapid fluid resuscitation, and applying vasopressors.The 2018 Surviving Sepsis Campaign bundle combined with the characteristics of children were reviewed, aiming at providing references for early goal oriented and cluster treatment, which in return to improve pediatric survival rate. Key words: Sepsis; Septic shock; Sepsis bundle
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