Abstract

Background Currently, non-depolarizing neuromuscular relaxant have been widely used in anesthesia for many surgical procedures. After administrating the relaxant, postoperative residual neuromuscular blockage (RNMB) ensues inevitably and mainly results in adverse respiratory events or even death occasionally. Objective Adequate reversal of neuromuscular blockage is crucial to decrease the incidence of postoperative RNMB and contribute to reduce the related complications. Content This article is aimed to review the updates on optimal neuromuscular management strategies, including the necessity of postoperative anticholinesterase agents, the most appropriate reversal opportunity and dose, as well as the new mode of selective reversal of RNMB.Trend The selective reversal of RNMB will reduce the occurrence of postoperative RNMB dramatically, and possibly even avoid RNMB. The novel preventing mode will lead the mainstream of preventing postoperative RNMB. Key words: Non-depolarizing neuromuscular blocking agents; Postoperative residual neuromuscular blockage; Reversal; Neostigmine; Sugammadex

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