Update on Noninvasive Diagnostic Imaging and Management of Nonmelanoma Skin Cancer

Abstract

The focus of this review is to present some of the new noninvasive diagnostic imaging tools and their use in conjunction with nonsurgical modalities that have been demonstrated to be effective for the treatment and prevention of nonmelanoma skin cancer (NMSC). Given the vast prevalence of NMSC and substantial associated morbidity, clinicians are working toward effective nonsurgical therapeutic options, including topical treatments, laser and photodynamic therapy, radiation as well as newer systemic treatment modalities. With this shift toward increasingly nonsurgical therapies comes the need to find new noninvasive ways to assess treatment efficacy, monitor treatment response, and detect subclinical residual disease. Recent developments in imaging modalities, including dermoscopy, optical coherence tomography, and reflectance confocal microscopy, are emerging as useful tools for diagnosis and treatment management of NMSC.