Abstract
Lymphoma classification has for years been confusing and at times exasperating, based solely on haematoxylin-and eosin-stained histological sections. Several major advances have allowed a new and less subjective classification to be developed:
 • use of immunostains
 • recognition that extranodal lymphomas are special
 • discovery of specific cytogenetic abnormalities in lymphomas
 • better understanding of lymphocyte physiology
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