Abstract
BackgroundGlyphosate, a commonly used pesticide, has been the topic of much debate. The effects of exposure to glyphosate remains a contentious topic. This paper provides an update to the existing literature regarding levels of glyphosate exposure in occupationally exposed individuals and focuses or reviewing all the available published literature regarding glyphosate exposure levels in children.MethodsA literature review was conducted and any articles reporting quantifiable exposure levels in humans published since January 2019 (the last published review on glyphosate exposure) were reviewed and data extracted and standardized.ResultsA total of five new studies reporting exposure levels in humans were found including 578 subjects. Two of these studies focused on occupationally exposed individuals while three of them focused on glyphosate exposure levels in children. Given the sparse nature of the new data, previously identified studies on exposure to glyphosate in children were included in our analysis of children’s exposure. The lowest average level of glyphosate exposure reported was 0.28 μg/L and the highest average exposure levels reported was 4.04 μg/L.ConclusionThe literature on glyphosate exposure levels, especially in children, remains limited. Without more data collected in a standardized way, parsing out the potential relationship between glyphosate exposure and disease will not be possible.
Highlights
The concerns associated with exposure to glyphosate, the active ingredient in the pesticide Round Up, have been a topic of much debate due to recent rulings and legal cases in the United States against the company that manufactures Round Up, Monsanto, which have concluded that the chemical may be carcinogenic [1]
We have endeavored to summarize what is known about exposure levels of glyphosate and its metabolite, Aminomethylphosphonic acid (AMPA)
Five studies were included in this updated review, which included two studies that focused on urinary glyphosate levels in children and three studies that focused on urinary glyphosate levels in occupationally exposed adults
Summary
The concerns associated with exposure to glyphosate, the active ingredient in the pesticide Round Up, have been a topic of much debate due to recent rulings and legal cases in the United States against the company that manufactures Round Up, Monsanto, which have concluded that the chemical may be carcinogenic [1]. The continued debate regarding the effects of glyphosate exposure makes establishing exposure levels in the general public a pressing public health issue, especially for the most vulnerable. Research shows that children are especially vulnerable to environmental toxins in general due to their small body mass; in the case of glyphosate, they are more likely to be exposed due to contact with dirt in playgrounds [7]. Children and occupationally exposed adults are the individuals most likely to experience harm from glyphosate exposure. This paper provides an update to the existing literature regarding levels of glyphosate exposure in occupationally exposed individuals and focuses or reviewing all the available published literature regarding glyphosate exposure levels in children
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