Abstract

组织学分级是骨和软组织肉瘤指导治疗和预测肿瘤预后的关键参数之一。目前WHO推荐的骨和软组织肉瘤组织学分级方法在临床实践工作中已经使用了几十年,有效地指导了临床进行相应治疗。随着分子遗传学技术的进步和对肿瘤精准治疗需求的提升,以肉瘤复杂指数(CINSARC)为代表的分子分级方法也被大家有所重视。本文详细介绍了骨和软组织肉瘤常用的分级方法及其局限性,并就CINSARC分子分级系统的构成、应用和进展进行了讨论,以期提升临床和病理医师对骨和软组织肉瘤分子分级的理解和认识。.

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