Abstract

CDC, the Food and Drug Administration (FDA), state and local health departments, and public health and clinical partners are investigating a multistate outbreak of lung injury associated with the use of electronic cigarette (e-cigarette), or vaping, products. In late August, CDC released recommendations for health care providers regarding e-cigarette, or vaping, product use associated lung injury (EVALI) based on limited data from the first reported cases (1,2). This report summarizes national surveillance data describing clinical features of more recently reported cases and interim recommendations based on these data for U.S. health care providers caring for patients with suspected or known EVALI. It provides interim guidance for 1) initial clinical evaluation; 2) suggested criteria for hospital admission and treatment; 3) patient follow-up; 4) special considerations for groups at high risk; and 5) clinical and public health recommendations. Health care providers evaluating patients suspected to have EVALI should ask about the use of e-cigarette, or vaping, products in a nonjudgmental and thorough manner. Patients suspected to have EVALI should have a chest radiograph (CXR), and hospital admission is recommended for patients who have decreased blood oxygen (O2) saturation (<95%) on room air or who are in respiratory distress. Health care providers should consider empiric use of a combination of antibiotics, antivirals, or steroids based upon clinical context. Evidence-based tobacco product cessation strategies, including behavioral counseling, are recommended to help patients discontinue use of e-cigarette, or vaping, products. To reduce the risk of recurrence, patients who have been treated for EVALI should not use e-cigarette, or vaping, products. CDC recommends that persons should not use e-cigarette, or vaping, products that contain tetrahydrocannabinol (THC). At present, CDC recommends persons consider refraining from using e-cigarette, or vaping, products that contain nicotine. Irrespective of the ongoing investigation, e-cigarette, or vaping, products should never be used by youths, young adults, or women who are pregnant. Persons who do not currently use tobacco products should not start using e-cigarette, or vaping, products.

Highlights

  • Rashid Njai, Office of the Director, Deputy Director for Non-Infectious Diseases, CDC; Jennifer Adjemian, Macarena Garcia, Kathleen Hartnett, Kristen Marshall, Aaron Kite Powell, Center for Surveillance, Epidemiology, and Laboratory Services, CDC; Adebola Adebayo, Minal Amin, Michelle Banks, Jordan Cates, National Center for Immunization and Respiratory Diseases, CDC; Maeh Al-Shawaf, Lauren Boyle-Estheimer, Peter Briss, Gyan Chandra, Karen Chang, Jennifer Chevinsky, Katelyn Chiang, Pyone Cho, Carla Lucia DeSisto, Lindsey Duca, Sumera Jiva, Charlotte Kaboré, John Kenemer, Akaki Lekiachvili, Maureen Miller, Yousra Mohamoud, Cria Perrine, Mays Shamout, Lauren Zapata, National Center for Chronic Disease Prevention and Health Promotion, CDC; Francis Annor, Vaughn Barry, Amy Board, Mary E

  • What is already known about this topic? Forty-nine states, the District of Columbia, and one U.S territory have reported 1,299 cases of lung injury associated with the use of electronic cigarette (e-cigarette), or vaping, products

  • What is added by this report? Based on the most current data, CDC’s updated interim guidance provides a framework for health care providers in their initial assessment, evaluation, management, and follow-up of persons with symptoms of e-cigarette, or vaping, product use associated lung injury (EVALI)

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Summary

Morbidity and Mortality Weekly Report

Update: Interim Guidance for Health Care Providers Evaluating and Caring for Patients with Suspected E-cigarette, or Vaping, Product Use Associated Lung Injury — United States, October 2019. In late August, CDC released recommendations for health care providers regarding e-cigarette, or vaping, product use associated lung injury (EVALI) based on limited data from the first reported cases (1,2). This report summarizes national surveillance data describing clinical features of more recently reported cases and interim recommendations based on these data for U.S health care providers caring for patients with suspected or known EVALI. Health care providers evaluating patients suspected to have EVALI should ask about the use of e-cigarette, or vaping, products in a nonjudgmental and thorough manner. To inform CDC’s updated interim clinical guidance, on October 2, 2019, CDC obtained individual expert perspectives on the evaluation and treatment of patients with suspected EVALI.

Clinical Evaluation for Patients with Suspected EVALI
Any respiratory
Management of Patients with Suspected EVALI
Clinical Care and Public Health Recommendations
Duration of hospital stay
Summary
Conflict of Interest
Lung Injury Response Clinical Working Group

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