Abstract
Optical oxygen sensors based on luminescent quenching are attractive as they are easily miniaturized, offer excellent sensitivity, and in the appropriate vehicle exhibit no cytotoxicity. However, these sensors must be energized by violet or blue wavelengths to report variations in oxygen content. These wavelengths experience high levels of absorption and scattering in biological tissue. Upconverting particles (UCPs) sidestep this limitation due to their ability to sequentially absorb two or more longer wavelength photons to emit a single, shorter wavelength photon. In this work, UCPs were utilized to emit blue light upon near infrared (NIR) absorption. A key advantage is that NIR light efficiently penetrates tissue barriers associated with potential biomedical applications. A layer of polycaprolactone (PCL) fibers containing Ru(dpp)3Cl2 was electrospun directly on top of a layer of fibers containing UCPs. We chose a bilayer configuration as it allowed direct examination of the ‘handshake’ interaction and investigation of significant design issues. Configurational aspects of the bilayer format were studied. Additionally, gaseous oxygen sensing following NIR excitation was confirmed. These upconverter-powered sensors were found to have a rapid response ( <0.25s).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
