Abstract
High open-pore content and high mechanical strength are important in Tissue engineering. However, an increase in one property is often at the expense of the other. This study reports a first-of-its-kind study using two-phase copolymers Poly (caprolactone-co-lactic acid) (PLCL) as a compatibilizer, combining in-situ fibrillation and microcellular foaming, thus preparing foams with high open-pore content and high mechanical properties. The porous foam scaffold promotes the adhesion and diffusion of endothelial cells and expedites scaffold endothelialization. Additionally, the enhanced open porosity of the foams augments the effectiveness of drug absorption and release, underscoring its significant potential for practical application.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
