UNVEILING A RARITY: LIGHT CHAIN DISEASE COINCIDING WITH PURE RED CELL APLASIA

Abstract

This paper presents a unique case report of concurrent Light Chain Disease (LCD) and Pure Red Cell Aplasia (PRCA), two rare hematological disorders seldom observed together. Light Chain Disease is a plasma cell disorder characterized by the overproduction of abnormal immunoglobulin light chains, while Pure Red Cell Aplasia is a rare bone marrow failure syndrome resulting in the selective reduction or absence of red blood cell precursors. The co-occurrence of these conditions poses diagnostic and therapeutic challenges due to their distinct pathophysiologies and clinical presentations. Through a detailed examination of the patient's medical history, diagnostic workup, and treatment outcomes, this case sheds light on the complexities associated with managing rare hematological disorders with overlapping manifestations.